When Lyle Villines learns his daughter has leukemia, he searches for a way to pay the huge medical bills that come with the condition. In desperation, he takes a well-paying, under-the-table job driving a delivery van. He doesn't know what the cargo is, but the pay is enough to make him ignore that for the sake of his child. Lyle questions his decision when he's hijacked on the interstate and left alive only so he can deliver a message to his employer. Turns out the load wasn't exactly legal. Nor was it insured, meaning he will have to pay for the loss by taking on a new job-cooking meth. Not only does it pay better, his boss says, it keeps him off the road. When Lyle objects, he's given a simple choice. He can either take the opportunity, or his family will suffer. Faced with no other option, the only thing to do is follow orders... and hope he can get out alive.
