Dr. Thea Sperelakis has always been an outsider. She has a brilliant medical mind and a remarkable ability to recall details, but her difficulty in dealing with hidden agendas and interpersonal conflicts has led her to leave the complex, money-driven dynamics of a hospital and to embrace working with the poor. Her father, Petros, is one of the most celebrated internal medicine specialists in the world and the founder of the cutting-edge Sperelakis Center for Diagnostic Medicine at Bostons sprawling, powerful Beaumont Clinic. When Petros is severely injured by a hit-and-run driver, no one thinks he will survive. Two of Petross other children, both physicians, battle Thea and their eccentric brother, Dimitri, by demanding that treatment for their father be withheld.