IgE Regulation: Molecular Mechanisms

IgE is the antibody isotype responsible for allergic reactions, a problem that affects 20% of the general population. An understanding of how, when and why IgE is produced is crucial to developing appropriate treatment for allergic disorders. This up-to-the-minute volume features: How T Cells direct IgE switchingIgE regulation in tissuesCytokine signal transduction and its role in isotype class switchingTranscription and switchingAntibody recognition of recombinant allergens and allergen-fragmentsIgE isoforms This unique book will be invaluable to both basic scientists and clinicians in immunology, molecular biology and allergies.